{"id":1411,"date":"2020-09-07T17:11:32","date_gmt":"2020-09-07T17:11:32","guid":{"rendered":"https:\/\/lorandparajdi.wordpress.com\/?page_id=1411"},"modified":"2023-07-17T15:57:58","modified_gmt":"2023-07-17T15:57:58","slug":"modeling-the-treatment-of-tumor-cells-in-a-solid-tumor","status":"publish","type":"page","link":"https:\/\/www.cs.ubbcluj.ro\/~lorand\/modeling-the-treatment-of-tumor-cells-in-a-solid-tumor\/","title":{"rendered":"Article no.1"},"content":{"rendered":"\n<p class=\"has-text-align-center\" style=\"font-size:28px\">Modeling the Treatment of Tumor Cells in a Solid Tumor<a style=\"display:block; font-size:13px; line-height:3.5em;\"><span style=\"color:#424547\" class=\"has-inline-color\">Research Paper, June 17, 2014 \/ Lorand Gabriel Parajdi<\/span><\/a><\/p>\n\n\n\n<p style=\"font-size:15px\">Published in <em>Journal of Nonlinear Science and Applications,<\/em> <em>7(3), 188\u2013195,<\/em> DOI:  <a rel=\"noreferrer noopener\" href=\"http:\/\/dx.doi.org\/10.22436\/jnsa.007.03.05\" target=\"_blank\"><span class=\"has-inline-color has-vivid-cyan-blue-color\">10.22436\/jnsa.007.03.05<\/span><\/a>, <em>2014<\/em>.<\/p>\n\n\n\n<p style=\"font-size:15px\"><img decoding=\"async\" loading=\"lazy\" width=\"267\" height=\"328\" class=\"wp-image-2308\" style=\"width: 18px;\" src=\"https:\/\/www.cs.ubbcluj.ro\/~lorand\/wp-content\/uploads\/2020\/10\/pdf_logo.png\" alt=\"\" srcset=\"https:\/\/www.cs.ubbcluj.ro\/~lorand\/wp-content\/uploads\/2020\/10\/pdf_logo.png 267w, https:\/\/www.cs.ubbcluj.ro\/~lorand\/wp-content\/uploads\/2020\/10\/pdf_logo-244x300.png 244w\" sizes=\"(max-width: 267px) 100vw, 267px\" \/><strong><span class=\"has-inline-color has-black-color\">&nbsp;&nbsp;The full paper is available on the JNSA website:<\/span><\/strong>    <a style=\"display:block;\"><\/a><a rel=\"noreferrer noopener\" href=\"https:\/\/www.isr-publications.com\/jnsa\/articles-1896-modeling-the-treatment-of-tumor-cells-in-a-solid-tumor\" target=\"_blank\"><span class=\"has-inline-color has-vivid-cyan-blue-color\">https:\/\/www.isr-publications.com\/jnsa\/articles-1896-modeling-the-treatment-of-tumor-cells-in-a-solid-tumor<\/span><\/a><\/p>\n\n\n\n<p style=\"font-size:15px\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-black-color\">Author:<\/mark><\/strong>  Lorand Gabriel Parajdi <\/p>\n\n\n\n<p style=\"font-size:15px\"><a style=\"display:block; color:#474747;\"><\/a>Department of Mathematics, &#8220;Babe\u015f\u2013Bolyai&#8221; University, Cluj-Napoca, Romania<\/p>\n\n\n\n<p style=\"font-size:15px\"><strong><span class=\"has-inline-color has-black-color\">Abstract:<\/span><\/strong>  It is well known that the theory of differential equations and some software packages are important tools for solving several actual problems from different real world domains. The novelty of this paper is the fact that the mathematical model of evolution of leukemic cells is adapted to the case of tumor cells, from a solid tumor, together with the treatment of the solid homogeneous tumor. Using the paper Dingli and Michor [D. Dingli, F. Michor, STEM-CELLS, 24 (2006), 2603-2610], we consider the model of evolution of a leukemic population for the case of solid tumors.<\/p>\n\n\n\n<p style=\"font-size:15px\"><strong><span class=\"has-inline-color has-black-color\">Subject Classification:<\/span><\/strong>  92B05, 34C60, 34A12<\/p>\n\n\n\n<p style=\"font-size:15px\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-black-color\"><strong>Keywords<\/strong>:<\/mark>  Cauchy problem; Mathematical model; Solid tumor; Tumor cells; System of differential equations.<\/p>\n\n\n\n<p style=\"font-size:15px\"><strong><span class=\"has-inline-color has-black-color\">Cite As:<\/span><\/strong>  Parajdi Lorand, Modeling the treatment of tumor cells in a solid tumor. J. Nonlinear Sci. Appl. (2014); 7(3):188&#8211;195.<\/p>\n\n\n\n<p style=\"font-size:15px\"><strong><span class=\"has-inline-color has-black-color\">References:<\/span><\/strong>  <br><strong><span class=\"has-inline-color has-black-color\">1.<\/span><\/strong>&nbsp; S. Arghirescu, A. Cucuianu, R. Precup, M. \u015eerban, <em>Mathematical Modeling of Cell Dynamics after Allogeneic Bone Marrow Transplantation in Acute Myeloid Leukemia<\/em>, Int. J. Biomath., 5 (<strong>2012<\/strong>), 18 Pages.  <a rel=\"noreferrer noopener\" href=\"https:\/\/www.worldscientific.com\/doi\/abs\/10.1142\/S1793524511001684\" target=\"_blank\"><span class=\"has-inline-color has-vivid-cyan-blue-color\">[Article]<\/span><\/a>       <br><br><strong><span class=\"has-inline-color has-black-color\">2<\/span>.<\/strong> &nbsp;A. Cucuianu, R. Precup, <em>A Hypothetical-Mathematical Model of Acute Myeloid Leukaemia Pathogenesis<\/em>, Comput. Math. Methods Med., 11 (<strong>2010<\/strong>), 49-65.  <a rel=\"noreferrer noopener\" href=\"https:\/\/www.hindawi.com\/journals\/cmmm\/2010\/217196\/\" target=\"_blank\"><span class=\"has-inline-color has-vivid-cyan-blue-color\">[Article]<\/span><\/a>       <br><br><strong><span class=\"has-inline-color has-black-color\">3<\/span>.<\/strong> &nbsp;D. Dingli, F. Michor, <em>Successful Therapy Must Eradicate Cancer Stem Cells<\/em>, STEM-CELLS, 24 (<strong>2006<\/strong>), 2603- 2610.  <a rel=\"noreferrer noopener\" href=\"https:\/\/stemcellsjournals.onlinelibrary.wiley.com\/doi\/full\/10.1634\/stemcells.2006-0136\" target=\"_blank\"><span class=\"has-inline-color has-vivid-cyan-blue-color\">[Article]<\/span><\/a>       <br><br><strong><span class=\"has-inline-color has-black-color\">4<\/span>.<\/strong>&nbsp; J. Guckenheimer, P. Holmes, <em>Nonlineat Oscillations, Dynamical Systems, and Bifurcation of Vector Fields<\/em>, Springer-Verlag, <strong>1983<\/strong>.  <a rel=\"noreferrer noopener\" href=\"https:\/\/books.google.ro\/books?hl=ro&amp;lr=&amp;id=XYIpBAAAQBAJ&amp;oi=fnd&amp;pg=PA1&amp;dq=Nonlinear+Oscillations,+Dynamical+Systems,+and+Bifurcations+of+Vector+Fields,+Springer-Verlag,+1983.&amp;ots=9P87K6OtQS&amp;sig=iTOMoUYsH9GmHp8es_7z2jDSrrw&amp;redir_esc=y#v=onepage&amp;q=Nonlinear%20Oscillations%2C%20Dynamical%20Systems%2C%20and%20Bifurcations%20of%20Vector%20Fields%2C%20Springer-Verlag%2C%201983.&amp;f=false\" target=\"_blank\"><span class=\"has-inline-color has-vivid-cyan-blue-color\">[Book]<\/span><\/a>       <br><br><strong><span class=\"has-inline-color has-black-color\">5<\/span>.<\/strong>&nbsp; C. Iancu, I. A. Rus, <em>Mathematical Modeling<\/em>, Transilvania Press, Cluj-Napoca <strong>1996<\/strong>.  <span class=\"has-inline-color has-vivid-cyan-blue-color\">[Book]<\/span>       <br><br><strong><span class=\"has-inline-color has-black-color\">6<\/span>.<\/strong>&nbsp; S. Lynch, <em>Dynamical Systems with Applications using Maple<\/em>, second edition, Birkh\u00e4user , Boston <strong>2009<\/strong>.  <a rel=\"noreferrer noopener\" href=\"https:\/\/books.google.ro\/books?hl=ro&amp;lr=&amp;id=VdJHAAAAQBAJ&amp;oi=fnd&amp;pg=PR13&amp;dq=S.+Lynch,+Dynamical+Systems+with+Applications+using+Maple,+second+edition,+Birkh%C3%A4user+,+Boston+2009&amp;ots=HTtunGEVBQ&amp;sig=Veb_Zcx4nXGaTNfM4kiQtsDJ4Jo&amp;redir_esc=y#v=onepage&amp;q=S.%20Lynch%2C%20Dynamical%20Systems%20with%20Applications%20using%20Maple%2C%20second%20edition%2C%20Birkh%C3%A4user%20%2C%20Boston%202009&amp;f=false\" target=\"_blank\"><span class=\"has-inline-color has-vivid-cyan-blue-color\">[Book]<\/span><\/a>      <br><br><strong><span class=\"has-inline-color has-black-color\">7<\/span>.<\/strong>&nbsp; L. Preziosi , <em>Cancer modelling and simulation<\/em>, Ed. Chapman &amp; Hall\/CRC, <strong>2003<\/strong>.  <a rel=\"noreferrer noopener\" href=\"https:\/\/books.google.ro\/books?id=FvUwTPUROm0C&amp;printsec=frontcover&amp;hl=ro&amp;source=gbs_ge_summary_r&amp;cad=0#v=onepage&amp;q&amp;f=false\" target=\"_blank\"><span class=\"has-inline-color has-vivid-cyan-blue-color\">[Book]<\/span><\/a>       <br><br><strong><span class=\"has-inline-color has-black-color\">8.<\/span><\/strong>&nbsp; R. Precup, M. A. \u015eerban, D. Trif , <em>Asymptotic stability for cell dynamics after bone marrow transplantation<\/em>, The 8th Joint Conference on Mathematics and Computer Science, Komarno, Slovakia, (<strong>2010<\/strong>), 1-11. <a rel=\"noreferrer noopener\" href=\"http:\/\/www.cs.ubbcluj.ro\/~macs\/2010\/2010-Preamble.pdf\" target=\"_blank\"><span class=\"has-inline-color has-vivid-cyan-blue-color\">[Book of Abstracts]<\/span><\/a>       <br><br><strong><span class=\"has-inline-color has-black-color\">9.<\/span><\/strong>&nbsp; R. W. Shonkwiler, J. Herod, <em>Mathematical Biology<\/em>, Ed. Springer, <strong>2009<\/strong>.  <a rel=\"noreferrer noopener\" href=\"https:\/\/books.google.ro\/books?hl=ro&amp;lr=&amp;id=nrOJbHjnQWgC&amp;oi=fnd&amp;pg=PR5&amp;dq=R.+W.+Shonkwiler,+J.+Herod,+Mathematical+Biology,+Ed.+Springer,+2009&amp;ots=VgbluieOKo&amp;sig=RuMlWSgy-MD178sNuwqCi5DNgyg&amp;redir_esc=y#v=onepage&amp;q&amp;f=false\" target=\"_blank\"><span class=\"has-inline-color has-vivid-cyan-blue-color\">[Book]<\/span><\/a>           <br><br><strong><span class=\"has-inline-color has-black-color\">10<\/span>.<\/strong> &nbsp;Z. Zeng , <em>Scientific Computing with Maple Programming<\/em>, <strong>2001<\/strong>.  <a rel=\"noreferrer noopener\" href=\"http:\/\/homepages.neiu.edu\/~zzeng\/340\/Fall16\/Notes\/340book.pdf\" target=\"_blank\"><span class=\"has-inline-color has-vivid-cyan-blue-color\">[Book]<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Modeling the Treatment of Tumor Cells in a Solid TumorResearch Paper, June 17, 2014 \/ Lorand Gabriel Parajdi Published in Journal of Nonlinear Science and Applications, 7(3), 188\u2013195, DOI: 10.22436\/jnsa.007.03.05, 2014. &nbsp;&nbsp;The full paper is available on the JNSA website: https:\/\/www.isr-publications.com\/jnsa\/articles-1896-modeling-the-treatment-of-tumor-cells-in-a-solid-tumor Author: Lorand Gabriel Parajdi Department of Mathematics, &#8220;Babe\u015f\u2013Bolyai&#8221; University, Cluj-Napoca, Romania Abstract: It is &hellip; <a href=\"https:\/\/www.cs.ubbcluj.ro\/~lorand\/modeling-the-treatment-of-tumor-cells-in-a-solid-tumor\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Article no.1<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.cs.ubbcluj.ro\/~lorand\/wp-json\/wp\/v2\/pages\/1411"}],"collection":[{"href":"https:\/\/www.cs.ubbcluj.ro\/~lorand\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.cs.ubbcluj.ro\/~lorand\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.cs.ubbcluj.ro\/~lorand\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cs.ubbcluj.ro\/~lorand\/wp-json\/wp\/v2\/comments?post=1411"}],"version-history":[{"count":15,"href":"https:\/\/www.cs.ubbcluj.ro\/~lorand\/wp-json\/wp\/v2\/pages\/1411\/revisions"}],"predecessor-version":[{"id":5413,"href":"https:\/\/www.cs.ubbcluj.ro\/~lorand\/wp-json\/wp\/v2\/pages\/1411\/revisions\/5413"}],"wp:attachment":[{"href":"https:\/\/www.cs.ubbcluj.ro\/~lorand\/wp-json\/wp\/v2\/media?parent=1411"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}